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Product Info Summary
| SKU: | A01173-1 |
|---|---|
| Size: | 100ul |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | IP, IF, IHC, WB, RIP |
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Product info
Product Name
Anti-PKM2 Antibody
SKU/Catalog Number
A01173-1
Size
100ul
Form
Liquid
Description
Boster Bio Anti-PKM2 Antibody catalog # A01173-1. Tested in WB,IHC,IF,IP,RIP applications. This antibody reacts with Human,Mouse,Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-PKM2 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A01173-1)
Host
Rabbit
Contents
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from human GCN2 around the phosphorylation site of T899.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
No cross reactivity with other proteins.
Reactive Species
A01173-1 is reactive to PKM in Human, Mouse, Rat
Applications
A01173-1 is guaranteed for IP, IF, IHC, WB, RIP Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
57.937kDa
Background of PKM
Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. AP-2-alpha is the only AP-2 protein required for early morphogenesis of the lens vesicle. Together with the CITED2 coactivator, stimulates the PITX2 P1 promoter transcription activation. Associates with chromatin to the PITX2 P1 promoter region.
ShunJiang Yu, J. Biol. Chem., May 2003; 278: 19597 - 19602.
TT Chen, Mol. Cell. Biol., Jun 1997; 17: 3056 - 3064.
Oscar B. Goodman, J. Biol. Chem., Oct 1995; 270: 23768.
Didier Jean, J. Biol. Chem., Jun 1998; 273: 16501
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:500-1:2000
IHC/IF: 1:50-1:200
IP/RIP: 1:50-1:200
Validation Images & Assay Conditions
There are currently no images for this product. We are working on uploading them please check back shortly or contact us to expedite our upload process for this antibody.
Protein Target Info & Infographic
Gene/Protein Information For PKM (Source: Uniprot.org, NCBI)
Gene Name
PKM
Full Name
Pyruvate kinase PKM
Weight
57.937kDa
Superfamily
pyruvate kinase family
Alternative Names
CTHBP; Cytosolic thyroid hormone-binding protein; MGC3932; OIP3; OIP-3; OIP3EC 2.7.1.40; Opa-interacting protein 3; p58; PK, muscle type; PK2; PK3; PK3PKM; PKM2; Pyruvate kinase 2/3; pyruvate kinase isozymes M1/M2; Pyruvate kinase muscle isozyme; pyruvate kinase, muscle; TCB; THBP1; THBP1p58; Thyroid hormone-binding protein 1; thyroid hormone-binding protein, cytosolic; Tumor M2-PK PKM CTHBP, HEL-S-30, OIP3, PK32, TCB, THBP1, p58, PKM pyruvate kinase M1/2 pyruvate kinase PKM|OPA-interacting protein 3|PK, muscle type|cytosolic thyroid hormone-binding protein|epididymis secretory protein Li 30|pyruvate kinase 2/3|pyruvate kinase isozymes M1/M2|pyruvate kinase muscle isozyme|pyruvate kinase, muscle|thyroid hormone-binding protein 1|thyroid hormone-binding protein, cytosolic|tumor M2-PK
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on PKM, check out the PKM Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for PKM: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-PKM2 Antibody (A01173-1)
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No publications found for A01173-1
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Recommended Resources
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